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Autoadhesion 현상을 이용한 PCL 세포 지지체 제작 KCI 등재

Fabrication of PCL scaffold using autoadhesion phenomenon

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한국기계기술학회지 (Journal of the Korean Society of Mechanical Technology)
한국기계기술학회 (Korean Society of Mechanical Technology)
초록

In this article, we proposed a novel technique to fabricate cell‐culturing scaffold, that is, the hollowcylinder‐ grain assembly technique. This technique uses hollow cylindrical particles with sub‐mm thickness. Firstly, we fabricate PCL (polycaprolactone) hollow cylinder with sub-mm thickness using lab-made stainless steel mold. After that, we put the above-mentioned fabricated particles into a metal mold of which temperature could be controlled with hot plate and heat insulation system. PCL particles in the metal mold could be assembled together without severe collapsing under adequate temperature and time. Consequently, we could fabricate scaffold or foam structure with interconnected‐porosity and observed surface of cross section of fabricated scaffold by SEM.

목차
Abstract
 1. 서론
 2. 세포 지지체(scaffold) 제작
  2.1 압축성형을 이용한 중공 원통 입자(hollow. cylinder particles) 제작
  2.2 Autoadhesion 을 이용한 세포지지체 제작
  2.3 전자주사현미경(SEM)을 이용한 표면 관찰
 3. 결론
 사사
 참고문헌
저자
  • 이세환(원광대학교 기계공학과(원)) | Se Hwan Lee
  • 조영삼(원광대학교 기계자동차공학부) | Young‐Sam Cho 교신저자
  • 최기평(원광대학교 기계공학과(원)) | Ghi Pyoung Choi
  • 안상현(원광대학교 기계공학과(원)) | Sang Hyun Ahn
  • 우창희(원광대학교 기계공학과(원)) | Chang Hee Woo