Kikuchi-Fujimoto disease (KFD) is a histocytic necrotizing lymphadenitis of cervical lymph node, which is usually combined with tenderness and fever presents mainly in women in their thirties. KFD has been rarely associated with SLE and the microscopic features of KFD can be similar to SLE. We described the case of a young man, originally diagnosed as having KFD by lymph node histology, who subsequently developed SLE with a skin rash, oral ulcer, hematologic and immunologic disorder and high titer of ANA. We recommend study of sexual and age-specific differences in clinical progress of KFD, and a long-term follow-up evaluation is also needed.

• 소유성(목포중앙병원 내과학 교실) | Yu Cheng Shu
• 당원광(목포중앙병원 내과학 교실) | Yuan Kuang Tang
• 김정한(목포중앙병원 내과학 교실) | Jeong Han Kim
• 강준태(목포중앙병원 내과학 교실) | Joon Tae Kang
• 채승석(목포중앙병원 내과학 교실) | Seung Seok Chae
• 명형준(목포중앙병원 내과학 교실) | Hyung Joon Myung Corresponding author