Primary adenocarcinoma is a rare neoplasm of the urinary bladder, constituting approximately 2.5% of all primary bladder malignancies. Signet ring cell variant is even rarer, constituting approximately 0.5% to 2.0% of all primary carcinoma of the urinary bladder. However, glandular differentiation in the urinary bladder is relatively more common than primary adenocarcinoma of the urinary bladder. Therefore, diagnosis of primary adenocarcinoma of the urinary bladder can be very challenging, but of significant clinical importance. We report on a case of adenocarcinoma with mucinous and signet ring cell differentiation in the bladder dome in a 49-year-old female.

• Inju Cho(Departments of Pathology, Chosun University College of Medicine)
• Sharon Lim(Departments of Pathology, Chosun University College of Medicine)
• Chul-Sung Kim(Departments of Urology, Chosun University College of Medicine)
• Sung-Chul Lim(Departments of Pathology, Chosun University College of Medicine) Corresponding Author