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Comparison of Valerenic Acids and Valepotriates Production According to the Culture Conditions for Cultured Roots of Valeriana fauriei var. dasycarpa Hara

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한국약용작물학회지 (Korean Journal of Medical Crop Science)
한국약용작물학회 (The Korean Society of Medicinal Crop Science)
초록

We established a practical method for rapid and large-scale production of Valeriana fauriei var. dasycarpa Hara roots by bioreactor culture and confirmed valerenic acids and valepotriates production. We also compared valerenic acids and valepotriates production patterns according to various media conditions. Among the media tested, B5 medium gave the maximum biomass production of 101 g fresh weight, which was a 5.03-fold multiplication rate obtained 4 weeks after inoculation of 20 g of fresh weight. The best production of total valerenic acids (7.86 mg/l) and valepotriates (8.96 mg/l) was B5 medium.

저자
  • Mei-Yang Li
  • Jun-Cheul Ahn
  • Kwang-Soo Kim
  • Ok-Tae Kim
  • Yoon-Jung Park
  • Baik Hwang