The study was performed to understand the effects of perilla and pine nut oils on hypercholesterolemia in cholesterol-fed male rats. All rats fed with the experimental diets for 3 weeks were decapitated to take serum. From the serum, the levels of total cholesterol, triglyceride, HDL-cholesterol, free cholesterol, phospholipid, lipoprotein and glucose were measured, and the results were summarized as follows. 1. The experimental diets supplemented with perilla and pine nut did not influence on the body weight and on amount of food intake, but decreased significantly total cholesterol level by the rate of 22-30% 2. The perilla diets decreased the β-/α-lipoprotein value from 0.99 to 0.50-0.51, but the pine nut diets decreased to 0.68-0.69. 3. The 10% diets of perilla and pine nut decreased the triglyceride concentration by the rate of 11-14%, but it was not significant difference. 4. The perilla diets increased the HDL-cholesterol level by the rate of 53-72%, and the pine nut diets 72-92%, but both of these diets did not influence on the free cholesterol concentration. 5. The perilla diets decreased phospholipid concentration by the rate of 20-23%, but it was not significant difference. 6. The diets of 10% perilla and 5% pine nut decreased significantly the free fatty acid concentration by the rate of 48% and 34% respectively. 7. The diets of 10% perilla and pine nut decreased a little the glucose level, but it was not significant difference.