The next generation small satellite-1 (NEXTSat-1) program has been kicked off in 2012, and it will be launched in 2016 for the science missions and the verification of space core technologies. The payloads for these science missions are the Instrument for the Study of Space Storms (ISSS) and NIR Imaging Spectrometer for Star formation history (NISS). The ISSS and the NISS have been developed by Korea Advanced Institute of Science and Technology (KAIST) and Korea Astronomy and Space science Institute (KASI) respectively. The ISSS detects plasma densities and particle fluxes of 10 MeV energy range near the Earth and the NISS uses spectrometer. In order to verify the spacecraft core technologies in the space, the total of 7 space core technologies (SCT) will be applied to the NEXTSat-1 for space verification and those are under development. Thus, the operation modes for the ISSS and the NISS for space science missions and 7 SCTs for technology missions are analyzed for the required operation time during the NEXTSat-1’s mission life time of 2 years. In this paper, the operational concept of the NEXTSat-1’s science missions as well as the verification of space core technologies are presented considering constraints of volume, mass, and power after launch.