This study was conducted to investigate the physiological activities of the water and ethanol extracts from three strains of Hypsizygus marmoreus. Largely, anti-hypertensive, anti-inflammatory, anti-diabetic, anti-tumorigenic activities were carried out. In addition, β-glucan contents were also measured. Mangadak 2 ho has the 36%(w/w) β-glucan contents, it is highest value of all strains. And it also showed highest inhibitory activities of angiotensin converting enzyme. GONJI No.6 highly inhibited releasing of nitric oxide from Raw 264.7. Anti-diabetic activity, the Hypsizygus marmoreus(from Japan) showed highest inhibitory activity on amyloglucosidase. MTT assay was performed on the anti-tumorigenic test. The cancer cell were used to HeLa, A549. repectively.

• Tae-Ho Kim(Department of Food Science & Biotechnology, Sungkyunkwan University)
• Hye-Sun Jung( Department of Food Science & Biotechnology, Sungkyunkwan University) | Hye-Sun Jung
• Ye-Sin Sim( Department of Food Science & Biotechnology, Sungkyunkwan University) | Ye-Sin Sim
• Young-Bok Yoo( Mushroom Research Division, National Institute of Horticultural & Herbal Science, RDA) | Young-Bok Yoo
• Dae-Hoon Jeon( Mushroom Research Staion, Gyeonggi-Do Agricultural Research and Extension Service) | Dae-Hoon Jeon
• Ki-Moon Park( Department of Food Science & Biotechnology, Sungkyunkwan University) | Ki-Moon Park