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Primary leiomyoma of the ovaries in a dog

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충북대학교 동물의학연구소 (Research Institute of Veterinary Medicine, Chungbuk National University)
초록

We would like to report a case of leiomyoma of the ovaries in a dog. Leiomyoma is commonly seen in the vagina in dogs. However, it is a very rare neoplasm in the ovaries. As there have only been a few reported cases, this report provides valuable information on veterinary medicine and pathology. Masses found in the ovaries need to be differentiated from other ovarian tumors. Therefore, we describe the gross, histopathological, and immunohistochemical features of a case of ovarian leiomyoma in a 10-year-old female Yorkshire Terrier dog. The mass on the right of the uterus was found accidentally by pelvic ultrasonography. Laparatomy revealed a large multi-nodulated ovarian mass. Grossly, cut surfaces of the mass showed multiple firm whitish nodules in the cortex and bloody loose connective tissue in the medulla. Histopathologically, the cortex of the mass was composed of spindle cells forming interlacing fascicles. The cells had elongated, blunt-ended nuclei and eosinophilic cytoplasm as detected by hematoxylin and eosin staining. Immunohistochemical stained sections were immunoreactive for α-smooth muscle actin and desmin but negative for vimentin and S-100. Therefore, differential diagnosis confirmed leiomyoma based on morphology and positive staining for α-smooth muscle actin and desmin.

저자
  • Hyeon-Wook Lee(Stem Cell Therapeutic Research Institute & Department of Pathology, College of Veterinary Medicine, Kyungpook National University)
  • Kyung-Ku Kang(Stem Cell Therapeutic Research Institute & Department of Pathology, College of Veterinary Medicine, Kyungpook National University)
  • Chang-Woo Min(Stem Cell Therapeutic Research Institute & Department of Pathology, College of Veterinary Medicine, Kyungpook National University)
  • Ah-Young Kim(Stem Cell Therapeutic Research Institute & Department of Pathology, College of Veterinary Medicine, Kyungpook National University)
  • Eun-Mi Lee(Stem Cell Therapeutic Research Institute & Department of Pathology, College of Veterinary Medicine, Kyungpook National University)
  • Eun-Joo Lee(Stem Cell Therapeutic Research Institute & Department of Pathology, College of Veterinary Medicine, Kyungpook National University)
  • Myeong-Mi Lee(Stem Cell Therapeutic Research Institute & Department of Pathology, College of Veterinary Medicine, Kyungpook National University)
  • Sang-Hyeob Kim(Stem Cell Therapeutic Research Institute & Department of Pathology, College of Veterinary Medicine, Kyungpook National University)
  • Soo-Eun Sung(Stem Cell Therapeutic Research Institute & Department of Pathology, College of Veterinary Medicine, Kyungpook National University)
  • Kyu-Shik Jeong(Stem Cell Therapeutic Research Institute & Department of Pathology, College of Veterinary Medicine, Kyungpook National University) Corresponding author