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Clinical variants of Guillain-Barré syndrome in children

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충북대학교 동물의학연구소 (Research Institute of Veterinary Medicine, Chungbuk National University)
초록

Guillain-Barre´ syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy most commonly characterized by rapidly progressive, essentially symmetric weakness and areflexia. This study examined clinical symptoms of clinical variants of GBS through a cerebrospinal fluid (CSF) study, nerve conduction (NCV) study, treatment, and prognosis. There were 16 children with GBS who visited our hospital from January 2011 to December 2013. Guillen-Barre´-like syndromes with transient synovitis were noted in three children. Clinical variants of GBS with acute demyelinating encephalomyelitis were observed in one child. Previous infections were noted in 16 children with Guillen-Barre´-like syndrome. There were ascending infections in 16 cases. Fifteen children showed symmetric infections, and one showed asymmetric infection. In NCV, slow waves were noted in two cases. We treated using intravenous immunoglobulin (IVIG) in four cases, IVIG with steroid in two, cases and supportive care in 10 (62.5%) cases. Five children treated with IVIG and 10 with supportive care management were completely improved.Our study suggests that supportive care is effective as a treatment for clinical variants of GBS. Further study is necessary for more patients.

목차
Introduction
 Materials and Methods
  연구대상
  통계학적 방법
 Results
  연령분포
  임상양상과 증상
  검사 결과
  진단
  치료
  경과
 Discussion
 Acknowledgements
 References
저자
  • Gi Youn Sim(Department of Pediatrics, Cheongju St. Mary’s Hospital)
  • Won Seop Kim(Department of Pediatrics, Chungbuk National University Hospital, Chungbuk National University, College of Medicine) Corresponding author