This research aims to develop and apply an English class program for elementary school students from multicultural families, in order to allow children from multicultural families who lack an understanding of language and culture (both their mother tongue and Korean) to participate successfully in regular English classes. For the purpose, 6 third-year students from multicultural special classes were observed and analyzed to identify difficulties experienced during regular English classes. Their difficulties were classified into lack of background knowledge and basic English words, insufficient use of learning strategies, lack of academic language understanding, and lack of self-confidence. To solve these difficulties, an English class program for elementary school students from multicultural families was developed and applied, based on the theory of multicultural education and the sheltered instruction model. The results are as follows: The introduction of an English class program for elementary school students from multicultural families is presumed to have had a positive effect on students’ English abilities and confidence. Based on this program, more special English teaching programs for the children from multicultural families are expected to be developed for their successful English learning.