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급성 두드러기를 주소로 내원한 소아의 혈청 총 IgE 수치와 알레르겐 특이항체 검사에 대한 연구

Study of Total IgE Level and Allergen Specific IgE in Children with Acute Urticaria

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The Medical Journal of Chosun University (조선대학교 의대논문집)
조선대학교 의학연구원 (Institute of Medical Science, Chosun University)
초록

Increased total IgE and eosinophil count levels are thought to provoke the occurrence of urticaria. The purpose of this study is to measure serum total IgE levels, specific IgE sensitization rates, and blood eosinophil count and to investigate the relationship between those factors. Among children who visited the Department of Pediatrics at Chosun University Hospital from January 2011 to December 2013, we retrospectively analyzed 63 patients with acute urticaria. Positive rates of the total serum IgE level, specific IgE, and blood eosinophil count were analyzed in patients with acute urticaria. A total of 63 patients were included in the study and the rate of males to females was 1: 0.8. Mean age of patients was 6.41±4.97 years (range 0-17 years). Among the subjects, 42.9% of patients showed an elevated serum total IgE and 63.5% of patients showed at least more than one allergen-specific IgE by MAST (multiple allergosorbent test). The mean number of allergens detected in positive patients was 2.42±2.56/patient. The serum total IgE and allergen specific IgE showed significant positive correlation (OR = 0.290, p=0.02). This study is meaningful as it revealed a positive correlation between serum total IgE and allergen
specific IgE in urticaria patients.

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저자
  • 조소여(조선대학교 의학전문대학원 소아청소년과학교실) | So Yeo Cho
  • 김은영(조선대학교 의학전문대학원 소아청소년과학교실) | Eun Young Kim
  • 노영일(조선대학교 의학전문대학원 소아청소년과학교실) | Young Il Rho
  • 문경래(조선대학교 의학전문대학원 소아청소년과학교실) | Kyung Rye Moon
  • 박영봉(조선대학교 의학전문대학원 소아청소년과학교실) | Yeong Bong Park
  • 양은석(조선대학교 의학전문대학원 소아청소년과학교실) | Eun Seok Yang Corresponding author