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Toxic Hepatitis with Liver Fibrosis in a 67-year-old Man Who took Fritillaria thunbergii Miquel

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The Medical Journal of Chosun University (조선대학교 의대논문집)
조선대학교 의학연구원 (Institute of Medical Science, Chosun University)
초록

A 67-year-old man visited our hospital with anorexia and abdominal discomfort after taking herb for 3 months. Abdominal computed tomograpy showed splenomegaly. Blood test showed elevation of serum alanine aminotransferase level, thrombocytopenia, and there was no viral or autoimmune hepatitis. Liver biopsy showed comprehensive fibrotic changes and necrosis on iver parenchyma. He recovered within 1 week after stopping the herb. There was no disease recurrence for 1 year. No case of toxic hepatitis by taking Fritillaria thunbergii Miquel has been reported. Thus, this case proved for the first time that Fritillaria thunbergii Miquel could cause drug induced liver injury.

목차
Introduction
 Case report
 Discussion
 References
저자
  • Young Min Rah(Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea) Corresponding author
  • Kyoung Min Moon(Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea)
  • Ahn Na Kim(Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea)