Primary progressive aphasia (PPA) is a progressive degenerative disorder that primarily affects language. Although the etiology of PPA has not been determined, autoimmune mechanism is known to be one possible pathophysiology. We investigate efficacy of steroid treatment in a patient diagnosed as both logopenic variant PPA and Sjögren's syndrome. After steroid treatment, her cognitive function, especially language ability showed improvement. And also, FDG-PET showed metabolic increase in the bilateral temporal lobe. However, on reassessment after stopping steroid treatment, her cognitive performance declined to pretreatment level.

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• IL Han Choo(Department of Neuropsychiatry, Chosun University Hospital, Gwangju, Republic of Korea, Department of Neuropsychiatry, School of Medicine, Chosun University, Gwangju, Republic of Korea) Corresponding author
• Ju Chang il(Department of Neurosurgery, Chosun University Hospital, Gwangju, Republic of Korea)
• Seung Gon Kim(Department of Neuropsychiatry, Chosun University Hospital, Gwangju, Republic of Korea, Department of Neuropsychiatry, School of Medicine, Chosun University, Gwangju, Republic of Korea)
• Eun Hyun Seo(Department of Neuropsychiatry, School of Medicine, Chosun University, Gwangju, Republic of Korea, The Division of Natural Medical Sciences, College of Health Science, Chosun University, Gwangju, Republic of Korea)
• Sang Hag Park(Department of Neuropsychiatry, Chosun University Hospital, Gwangju, Republic of Korea, Department of Neuropsychiatry, School of Medicine, Chosun University, Gwangju, Republic of Korea)
• Sang Hoon Kim(Department of Neuropsychiatry, Chosun University Hospital, Gwangju, Republic of Korea, Department of Neuropsychiatry, School of Medicine, Chosun University, Gwangju, Republic of Korea)
• Woon Yeong Park(Department of Neuropsychiatry, Chosun University Hospital, Gwangju, Republic of Korea)