All living organisms use memory and oblivion algorithms considering the estimated lifetime and the changes in the ambient environment. Because of the expected lifetime of a bridge is similar to the human’s one, if a bridge uses the same algorithm of human memory, the abnormal responses of the structure can be easily detected. This paper introduces unfamiliarity index (UFI) that calculated from the FFT results of the short term timeline acceleration responses. If this algorithm, which can detect an abnormal behavior from the maximum constant signal, is used to the terminal sensors of an structure, more accurate safety control criteria will be prepared efficiently.