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하이브리드 스캐폴드의 간헐적인 기계적 자극에 대한 영향 KCI 등재
The Effect of Intermittent Mechanical Stimulation on Hydrogel Scaffold
이승재, 최성규, 박정훈, 강상순, 고태조, 이인환
- 언어ENG
- URLhttps://db.koreascholar.com/Article/Detail/291769
4,000원
한국기계항공기술학회지(구 한국기계기술학회지)
(Journal of the Korean Society of Mechanical and Aviation Technology)
제15권 제6호 (2013.12)
pp.1007-1012
pp.1007-1012
한국기계항공기술학회(구 한국기계기술학회)
(Korean Society of Mechanical Technology)
초록
Mechanical stimulation has been reported to improve cell growth in bone and cartilage regeneration. Various research groups have described their own bioreactors that stimulate cell-seeded scaffolds. We have developed a bioreactor capable of applying controlled compressive loading to a cell-encapsulated agarose hydrogel. To compare the effect of mechanical stimulation on agarose hydrogel, we used one control group (static mode) and five experimental groups. The results show that the intermittent_3sec conditions improve proliferation of cells better than the other conditions studied.
키워드
Mechanical stimulation기계적 자극Hydrogel scaffold하이브리드 인공지지체Agarose아가로즈Tissue engineering조직공학Bioreactor동적배양장치
목차
Abstract
1. Introduction
2. Fabrication of Bioreactor
3. Materials and Methods
3.1 Cell culture
3.2 Fabrication of hydrogel scaffold
3.3 Modes of compression stimulation
3.4 Analysis of flow proliferation and fluorescence images
4. Results and Discussions
5. Conclusion
Acknowledgment
References
1. Introduction
2. Fabrication of Bioreactor
3. Materials and Methods
3.1 Cell culture
3.2 Fabrication of hydrogel scaffold
3.3 Modes of compression stimulation
3.4 Analysis of flow proliferation and fluorescence images
4. Results and Discussions
5. Conclusion
Acknowledgment
References
저자
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