This study carried out a series of seismic tests to elucidate the difference of movements between two buildings with or without masonry infilled wall in reinforced concrete frames which have no quake proof plan. Both of the experimental buildings showed irreversible deformity at low drift ratio of 0.6%. The strength and stiffness of the building with masonry infilled wall were higher than those of the building without masonry infilled wall, while the ductility of the former being lower than that of the latter. Thus it led to more brittle tendency of the former.