To evaluate the stress-strain relationship of HVFA(High Volume Fly Ash) concrete, experiments were performed according to the ratio of fly ash usage and concrete compressive strength. Test results were shown that elasticity modulus of HVFAC was influenced by compressive strength, elasticity modulus and fly ash usage ratio. And the existing equation of stress-strain relationship had a large difference. So, new equation of stress-strain relationship for HVFAC was proposed, and the proposed results had a good correlation with test results