Currently, implants are widely used in dental and medical fields. Especially dental implants are widely used for reconstruction of oral and maxillofacial defects. Many researcher's had studied for raising the osseointegration through various method. It was reported high success rate. Also they study the enhancing the speed of bone remodelling and osseointegration. Low level laser therapy is introduced one of the methods to accelerate the speed of bone remodelling and osseointegration. The purpose of this study was to evaluate the effect of diode laser irradiation about to raise ossoeintegration. Twenty four New Zealand white rabbits which were about 3Kg were used for experiment. Two implants were implanted same side of rabbits tibia. Diode laser was irradiated 1cm diameter, 0.5 watt power, 1 minute duration at periphery of one of implants. Eight rab b its were sacrificed every 2, 4, 8 weeks, made undecalcified sample. We investigated in the undecalcified samples histological and histomorphometrc analysis by light microscope. The results were as follows. 2 weeks, 4 weeks, 8 weeks experimental groups which were showed rapid bone remodelling than control groups. They showed many difference especially in early healing time. Bone Implant contact rate were 47% in 2 weeks experimental group. 28% in 2 weeks control groups, 82% in 4 weeks experimental groups, 62% in 4 weeks control groups, 98% in 8 weeks experimental groups and 84% in 8 weeks control groups then experimental groups show statistically significant difference(p＜0.05). Bone remodelling area rate inside the implant threads were 49% in 2 weeks experimental groups. 31% in 2 weeks control groups, 90% in 4 weeks experimental groups, 82% in 4 weeks control groups, 99% in 8 weeks experimental groups and 97% in 8 weeks control groups then 2,4 weeks experimental groups show statistically significant difference(p＜0.05). Implant-bone contact length rate and bone remodelling area rate were no significant difference of linear regression equation of control and experimental groups then bone remodelling were different at early healing time but there were no differences of time changes. According to above results, one of the low level lasers diode laser irradiation was effected on the volume of new bone formation in implant interface and between the implants threads. Low level laser irradiation were helpful for initial stage of bone remodelling.

I. 서론
 II. 연구재료 및 방법
  1. 실험재료
  2. 실험방법
 III. 결과
  1. 조직학적 소견
  2. 조직계측학적 분석
  3. 통계분석
 
IV. 총괄 및 고찰
 V. 결론
 VI. 참고문헌

• 지성원(인하대학교 대학원 의학과(치과학전공)) | Sung Won Ji
• 오남식(인하대학교 대학원 의학과(치과학전공)) | Nam Sik Oh correspondence
• 천재식(단국대학교 치과대학 구강생리학교실) | Gae Sig Chun