In recent days, there is much interest in the biocidal activity of silver since silver is known to be safe and effective as disinfectant and biocidal material against bacteria and viruses. There is also increased interest in the nano-sized silver particles which can be used as effective bactericidal material. The purposes of this study were to investigate the effect of silverized elastomers on growth of oral pathogenic microorganisms, including Streptococcus mutans, Fusobacterium nucleatum, Porphyromonas gingivalis by comparing with conventional non-silverized elastomers. The antibacterial efficacy of silverized elastomer against oral pathogenic microbes was investigated by modified disk diffusion test and growth inhibition test. In modified disk diffusion test, silverized elastomer showed no antibacterial activity against S. mutans, F. nucleatum and P. gingivalis, In culture medium, the growth of S. mutans, F. nucleatum, P. gingivalis was not inhibited by silverized elastomer. Silverized elastomer exhibited no bacteriostatic and/or bacteriocidal effects against some experimental strain.nd clinical indications and diseases.

Ⅰ. 서론
 II. 재료 및 방법
  1. 연구 재료
  2. 실험 대상 균주 및 배양 조건
  3. 항균활성 측정 시험(Disk diffusion test)
  4. 구강 내 병인균의 생육에 대한 은이온의 영향(Growth Inhibition Test)
 III. 연구 결과
  1. 항균활성 측정 시험-Disk diffusion test
  2. 구강 내 병인균의 생육에 대한 은이온의 영향-Growth Inhibtion Test
  3. 은이온 방출 고무결찰의 표면 양상 관찰-Scanning Electron Microscope
 IV. 총괄 및 고찰
 V. 결 론
 VI. 참고문헌

• 원윤아(고려대학교 임상치의학대학원 치과교정학과) | Yoon Ah Won
• 이동렬(고려대학교 임상치의학대학원 치과교정학과) | Dong Yul Lee
• 이진용(경희대학교 치의학전문대학원 미생물학교실) | Jing Yong Lee
• 김민지(이화여자대학교 임상치의학대학원 치아교정학과) | Min ji Kim
• 김예진(고려대학교 임상치의학대학원 치과교정학과) | Yae jin Kim
• 임용규(고려대학교 임상치의학대학원 치과교정학과) | Yong Kyu Lim correspondence