The purpose of this study is to identify the relation between predominant period of earthquake and acceleration characteristics of domestic high-rise buildings. First, we gathered and classified the real earthquake waves through response spectrum method. Second, we performed seismic response analysis and analyzed the result. The conclusion is as follows. In the case of predominant period range from 1.0 to 4.0 which has relatively less probability, the damage can be concentrated on buildings from 20 to 60 story.