This study mainly focuses on presenting a rational procedure of assessing target reliability level of nuclear containment. The target reliability level can be obtained by considering LCC(Life Cycle Cost) of damage and operation. The LCC evaluation results in the different environmental situations. It is verified that this deviation of LCC can be adjusted by selecting the proper initial target reliability. In addition, slight increase of initial target reliability for the nuclear containment aiming a longer service life, therefore, the total expected loss during the extended service years can be maintained in the same level as the total loss expected in the 20-year service life for the existing containment structures.