논문 상세보기
A strategy for analysis of soybean genome resequencing data
Soybean is one of the most important crop plants used for seed protein and oil content that has undergone substantial phenotypic and physiological changes during domestication. Thanks to the advent of the next-generation sequencing platforms, genome sequences of many major crop plants including soybean and maize have been unraveled. We have resequenced the genomes of 10 cultivated soybean and 6 accessions of their wild progenitors (Glycine soja) selected from the Korean soybean germplasm to >15 × raw data coverage. We have investigated genome-wide variation patterns in soybean and obtained millions of high-quality single nucleotide polymorphisms (SNPs). Further analyses of the extracted SNPs including population structure analysis, introgressions, linkage disequilibrium, and reduction of diversity are ongoing in order to provide an unprecedented opportunity to finely resolve the domestication history of cultivated soybean. At the same time, we have conducted a comparison study between the Williams 82 soybean reference genome sequence and a genetic map. Here, I will present our current analysis status of the soybean genome resequencing data. Then, I present our recent progresses in the understanding of dynamic genetic features of soybean chromosome revealed by comparison of genetic and sequence-based physical maps in which we have used a portion of our resequencing data to substantiate putative introgression region detected during the construction of a genomewide soybean genetic map.
