The aim of this study was to examine the ameliorating effect of black ginseng on the growth of the HepG2 cell transplanted tumor in BALB/c nude mice. 27 male BALB/c nude mice (all six weeks old) were randomly divided into three groups: the control group, the first treatment group (HepG2300RG, using 300 mg/kg red ginseng), and the second treatment group (HepG2300BG, using 300 mg/kg black ginseng). The HepG2300BG in the HePG2 cells showed increased mean survival time than that of red ginseng group. The size and volume of the tumor in the 300BG group showed significant reduction compared to those of the HepG2300RG group (p<0.05). The body weight and liver weight of the HepG2300RG group was not significantly different with control and HepG2300BG group. The serum levels of ALT and AST in the HepG2300RG and HepG2300BG group were significantly lower than those of the control group. In conclusion, these results suggest that the black ginseng may have possible anti-tumor activities.

Abstract
 서 론
 재료 및 방법
  1. 실험재료
  2. 진세노사이드 Rg3 함량 분석
  3. 세포 배양
  4. 암세포주
  5. 실험동물
  6. 종양이식모델
  7. 적출 고형암의 중량 및 부피 측정
  8. 평균 생존시간 및 생존 증가율 측정
  9. 체중 및 체중에 대한 상대적 간 무게 측정
  10. 혈청 AST와 ALT 함량 측정
  11. 통계처리
 결과 및 고찰
  1. Ginsenoside Rg3 함량
  2. 평균 생존시간 및 생존 증가율
  3. 고형암의 중량 및 부피
  4. Rg3와 실험동물의 평균 생존시간, 고형암 중량 및 고형암 부피와의 상관관계
  5. 체중 및 체중에 대한 상대적 간 무게
  6. 혈청 AST와 ALT 함량
 요약 및 결론
 References

• 강신정(중부대학교 한방제약과학과) | Shin-Jyung Kang
• 한정순(경기대학교 대체의학대학원) | Jung-Soon Han
• 김애정(경기대학교 대체의학대학원) | Ae-Jung Kim Corresponding author