논문 상세보기

Role of Golgi Apparatus on Regulation of Sec61β, COPG2 and Epidermal Growth Factor during Oocyte Maturation

  • 언어ENG
  • URLhttps://db.koreascholar.com/Article/Detail/299967
구독 기관 인증 시 무료 이용이 가능합니다. 4,000원
한국동물번식학회 (The Korean Society of Animal Reproduction)
초록

The oocyte undergoes various events during maturation and requires many substances for the maturation process. Various intracellular organelles are also involved in maturation of the oocyte. During the process glucose is essential for nuclear and cytoplasmic maturation, and adenosine triphosphate is needed for reorganization of the organelles and cytoskeleton. If mitochondrial function is lost, several developmental defects in meiotic chromosome segregation and maturation cause fertilization failure. The endoplasmic reticulum, a store for Ca2+, releases Ca2+ into the cytoplasm in response to various cellular signaling molecules. This event stimulates secretion of hormones, growth factors and antioxidants in oocyte during maturation. Also, oocyte nuclear maturation is stimulated by growth factors such as epidermal growth factor. This review summarizes roles of organelles with focus on the Golgi apparatus during maturation in oocyte.

목차
ABSTRACT
 INTRODUCTION
 OOCYTE MATURATION
 RELATION OF OOCYTE MATURATIONAND GA
 CONCLUSION
 REFERENCES
저자
  • Choon-Keun Park(College of Animal Life Science, Kangwon National University) Corresponding author
  • Eunsong Lee(College of Veterinary Medicine, Kangwon National University)
  • Seung Tae Lee(College of Animal Life Science, Kangwon National University)
  • Seunghyung Lee(College of Animal Life Science, Kangwon National University)
  • Sang-Hee Lee(College of Animal Life Science, Kangwon National University)
  • Hae-In Oh(College of Animal Life Science, Kangwon National University)