The aim of this study was to evaluate the effects of animal-assisted activity on social aspects among inpatients with schizophrenia. Four participants including 2 males and 2 females were assigned to the animal-assisted activity program treatment group with therapy dog. A weekly animal-assisted activity program was arranged for patients in the treatment group for 10 weeks. The analysis assessing social skills was completed the week before and the week after the animal-assisted activity. The treatment group showed improvement on the social skills. The results of this study showed that animal-assisted activity can promote improvements in many clinical aspects among inpatients with schizophrenia. Therefore, animal-assisted activity should be integrated into the treatment of institutionalized patients with schizophrenia.