Powder compaction is a continually and rapidly evolving technology where it is a highly developed method ofmanufacturing reliable components. To understand existing mechanisms for compaction, parameter investigation isrequired. Experimental investigations on powder compaction process, followed by numerical modeling of compaction arepresented in this paper. The experimental work explores compression characteristics of soft and hard ductile powdermaterials. In order to account for deformation, fracture and movement of the particles, a discrete-finite element analysismodel is defined to reflect the experimental data and to enable investigations on mechanisms present at the particlelevel. Effects of important simulation factors and process parameters, such as particle count, time step, particle discret-ization, and particle size on the powder compaction procedure have been explored.