The purpose of this study was to evaluate the effect of essential oil on wound healing rate, an epithelial attachment and collagen density in wound induced rat. This study was a 2×3 factorial design. Factors were treatment period (4 day and 8 day) and treatment type [saline (0.9% NaCl), tyrothricin, mixture of tea-tree, rosemary and melissa oil]. The samples were 24 rats with wound and randomly assigned to six groups of four rats per group. The dependent variables such as a wound healing rate, an epithelial attachment and a collagen density were measured. Dependent variables were statistically significant difference by the two treatment periods and the three treatment types (p<.001). There were not statistically significant interactions between treatment periods and treatment type in all dependent variables (p>.05). These findings will be provide bases to develope effective interventions for patients who have wound to manage their wound.

Ⅰ. 서론
 Ⅱ. 연구방법
  1. 연구설계
  2. 연구대상
  3. 실험방법
  4. 자료분석 방법
 Ⅲ. 결과 및 고찰
  1. 생육 저해환 측정
  2. 창상치유율
  3. 표피간격 및 콜라겐 밀도
  4. H-E 염색결과
 Ⅳ. 적요
 Ⅴ. References

• 장혜숙(전주대학교) | Hye Sook Jang
• 서영미(전주대학교) | Young Mi Seo Corresponding author