The aim of this study is to examine of the cluster approach to ensure high rates of innovation, information and communication enterprises of information technology cluster in order to enhance the competitiveness of regions. Keeping with the previous literature, the present research determined that the novelty of the problem, concerning of the creation IT clusters as drivers of new generation, i.e. a kind of platform of "startup accelerators" through the creation of previously not existing in the country high-tech industries and sectors of the economy. The study employs system approach involves to determine prospective directions of the formation of clusters of IT industry, also applies structured approach to shows relationships between elements of cluster systems (participants of cluster), as well as focusing on some aspects of cluster development such as networking. Based on this analysis we have proposed to create clusters in regions, which can play the role of translator’s innovations at the periphery of the country. This research shows that formation of IT clusters is one of the most successful tools to avoid of dependence of Kazakhstan from raw materials.