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Effects of Low intensity Cardiac Rehabilitation Exercise on Weight and Histological Changes of Rat Models with Acute Myocardial Infarction KCI 등재

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  • URLhttps://db.koreascholar.com/Article/Detail/316407
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국제물리치료연구학회 (International Academy of Physical Therapy Research)
초록

The purpose of the study was to investigate effects of Low intensity cardiac rehabilitation, using a treadmill, on the myocardial structure. We identified the effects by analyzing changes in the rats' weights and the results of biopsies. Twenty Sprague-Dawley male rats, 50 weeks old, were randomly divided into the exercise group and the control group. myocardial infarction( MI) was induced by ligaturing their left anterior descending artery. After the acute MI induction, two rats of each group began to fall dead, therefore, eight of each group completed at the end of the experiment. We used treadmills for animals for the exercise group. This exercise group performed 30 minutes of exercise five times per week for six weeks, while the control group did not perform any exercise. No statistically significant differences in weight were found in within group comparison and between group comparison. Furthermore, we observed histological changes in the myocardium using Hematoxylin & Eosin and Masson's trichrome staining in both groups. Low-intensity exercise inhibited myocardial fibrosis, may serve as a reference in the cardiopulmonary field, which plays a role in rehabilitating patients with cardiac disorders, including acute MI.

목차
INTRODUCTION
 METHODS
  Subjects
  Exercise program
  Measurement of body weight
  Histological changes
  Data Analysis
 RESULTS
  Changes in body weight
  Histological changes
 DISCUSSION
 CONCLUSIONS
 REFERENCES
저자
  • Sung Ha Ji(Department of Physical Therapy, Jungang Seng Korean Oriental Hospital)
  • Ki Jong Kim(Department of Physical Therapy, Cheongam College)