Toxicity assessment of heavy metals (As, Cr and Pb) has been investigated by using the rate of survival and population growth(r) of marine rotifer, Brachionus plicatilis. The survival rate was determined after 24 hours of exposure to As, Cr and Pb. As and Cr reduced survival rate in dose-dependent manner and a significant reduction were occurred at concentration of greater than 30 and 150 mg L-1, but Pb had no effect on survival rate. The r was determined after 72 hours of exposure to As, Cr and Pb. As, Cr and Pb reduced r in dose-dependent manner and a significant reduction were occurred at concentration of greater than 5, 25 and 50 mg L-1. The toxicity of heavy metals were ranked As>Cr>Pb, with EC50 values of 12.98, 82.34 and 110.14 mg L-1, respectively. The no-observed-effect-concentration (NOEC) of r in As, Cr and Pb exposure were 1, 12.5 and 50 mg L-1, respectively. The lowest-observed-effect-concentration (LOEC) of r in As, Cr and Pb exposure were 5, 25, and 50 mg L-1, respectively. From the results, the concentration of As, Cr and Pb (greater than 5, 25 and 50 mg L-1, respectively) have toxic effect on the r of B. plicatilis in natural ecosystems. These results (including NOEC and EC50) might be useful for the mixing toxicity assessment and toxic guide line of heavy metals in marine ecosystems.

서 론
 재료 및 방 법
  1. 시험생물
  2. 중금속 농도 조성
  3. 생존율
  4. 개체군 성장률
  5. 통계분석
 결 과
  1. 중금속이 생존율에 미치는 영향
  2. 중금속이 개체군 성장률에 미치는 영향
  3. 생존율 및 개체군 성장률을 이용한 독성평가
 고 찰
 적 요
 References

• 이주욱(국립수산과학원 서해수산연구소 해양생태위해평가센터) | Ju-Wook Lee
• 류향미(국립수산과학원 서해수산연구소 해양생태위해평가센터) | Hyang-Mi Ryu
• 허승(국립수산과학원 서해수산연구소 해양생태위해평가센터) | Seung Heo
• 황운기(국립수산과학원 서해수산연구소 해양생태위해평가센터) | Un-Ki Hwang Corresponding author