Zika virus (ZIKV) is an ongoing global public health emergency with 74 countries (Sep. 19 2016) and territories reporting evidence of ZIKV transmission since 2015. Total 14 cases of Zika have been reported since January 2016 and all cases have been suspected as infections by mosquito bite on overseas. Vector control strategy of comprehensive national Zika control strategies will be presented on this presentation. To efficiently control Ae. albopictus when Zika inflow into ROK, nine ministers of government held on Zika countermeasure meeting, checked preparatory attitudes and assigned roles of each minster for Zika control. Korea guidelines for Ae. albopictus control were distributed to local governments and related ministers of government and vector control agents in all local government were educated by vector control experts. To block transmission of Zika virus by mosquito bite from overseas travel-associated patients Zika patients in ROK, vector monitoring and control were carried out at surroundings near residences of patients and decreased vector population density.