Sickness absence is one of the most important indicators for worker's health and occupational safety and health performance. Sickness absence is primarily depended upon sickness but psycho-social factors in workplace may moderate sickness absence. Even though worker is falling into illness, sickness absence can be prevented by job satisfaction. In Korea it is very difficult to find research output about the association of sickness absence with job satisfaction. This study is planned to investigate the effect of job satisfaction on sickness absence. The third Korean Working Conditions Survey done by Occupational Safety and Health Research Institute in 2011 was used to anlayze by logistic regression analysis. The result has shown that job satisfaction has statistically significant effect on sickness absence and simultaneously diminish the effect of symptoms experience on sickness absence. The effect of job satisfaction is greater in short term sickness absence that in long term sickness absence. This study has some limitation because of the cross sectional data of Korean Working Conditions Survey. In future, sophisticated statistical analysis may be done with modelling.