Secondary metabolites isolated from Actinomycete have been studied to find potent pest control agents as their insecticidal and growth inhibitory activities. In order to investigate novel insecticidal compounds, second metabolites from 363 Actinomycete isolates were evaluated for their insect growth regulatory activities. Among them, ethyl acetate extracts from ten Streptomyces spp. showed high level of Juvenile hormone antagonist activity. In addition, their insecticidal activities were tested against larvae of Aedes albopictus, Plutella xylostella and Laodelphax striatellus. These results suggested that secondary metabolites from Streptomyces spp. could be used for development of novel IGR-based insecticides.

• Jong Hoon Kim(Department of Agricultural Biotechnology, Seoul National University)
• Jae Young Choi(Research Institute for Agriculture and Life Sciences, Seoul National University)
• Min Gu Park(Department of Agricultural Biotechnology, Seoul National University)
• Ra Mi Woo(Department of Agricultural Biotechnology, Seoul National University)
• Seok-Hee Lee(Department of Agricultural Biotechnology, Seoul National University)
• Ying Fang(Department of Agricultural Biotechnology, Seoul National University)
• Dong Hwan Park(Department of Agricultural Biotechnology, Seoul National University)
• Bo Ram Lee(Department of Agricultural Biotechnology, Seoul National University)
• Woo Jin Kim(Department of Agricultural Biotechnology, Seoul National University)
• Yeon Ho Je(Department of Agricultural Biotechnology, Seoul National University)