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아로니아 추출물의 항산화 및 항염증 효과

Role of Aronia melanocarpa ‘Viking’ Extracrs as Antioxidant and Anti-Inflammatory Agent

  • 언어ENG
  • URLhttps://db.koreascholar.com/Article/Detail/326190
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한국약용작물학회 (The Korean Society of Medicinal Crop Science)
초록

Background : Aronia melanocarpa ‘Viking’ known as black chokeberry, is a species of rosaceae family. Chokeberry is high in flavonoid/anti-oxidants as well as high in vitamins and minerals. Black chokeberry contains high amount of polyphenols, especially anthocyanins. Methods and Results : The aim of this study is to figure out the antioxidant and anti-inflammatory property of Aronia melanocarpa ‘Viking’ (AMV) for both water and ethanol extract. The extracts have been tested to assess the 1, 1-diphenyl-2-picryl-hydrazyl (DPPH), 2,2ʹ-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and nitrite scavenging activity. We have also evaluated the reducing power activity of AMV. AMV extracts showed a good radical scavenging activity on DPPH and ABTS free radical. The DPPH radical scavenging activity ranges from 20.59% - 80.12% and 26.12% - 95.59% for water and ethanol extract, respectively. The total phenolic and flavonoid contents have also been estimated in this study. Moreover, to appraise the anti-inflammation property we examined cell viability and inhibition of nitric oxide (NO) production by using the lipopolysaccharide-treated RAW 264.7 macrophage cell line. The extracts showed no cytotoxic effects on RAW 264.7 cells. Conclusion : According to the results, we suggest AMV contains noticeable antioxidant properties and could be source of natural antioxidant substances.

저자
  • Ghosh Mithun(College of Biomedical and Health Science, Department of Life Science, Konkuk University) | 미툰 고쉬
  • Young Min Lee(College of Biomedical and Health Science, Department of Life Science, Konkuk University) | 이영민
  • In Sook Kim(College of Biomedical and Health Science, Department of Life Science, Konkuk University) | 김인숙
  • Seong Min Hong(College of Biomedical and Health Science, Department of Life Science, Konkuk University) | 홍성민
  • Taek Hwan Lee(AG-Health Research Center) | 이택환
  • Beong Ou Lim(College of Biomedical and Health Science, Department of Life Science, Konkuk University) | 임병우 Corresponding author