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비타민나무 잎과 열매 복합물의 생리활성
Biological Activities of the Mixture of Hippophae rhamnoides L. Leaf and Fruit
- 언어ENG
- URLhttps://db.koreascholar.com/Article/Detail/326192
Background : Sea buckthorn (Hippophae rhamnoides L.) was used as medicinal plant in Tibetan and Mongolian traditional medicines. It has been recognised as a versatile nutraceutical crop with diverse uses for the treatment of diseases, such as gastric ulcers, lung disorders, cardiovascular diseases, mucosal injuries and skin disorders. Physiological research on mixture of sea buckthorn leaf and fruit have not be reported. Therefore, in this study, using sea buckthorn mixture, antioxidant and anti-inflammatory effects were determined. Methods and Results : The experiment was carried out using 11 samples (100% leaf extract - 100% fruit juice powder). The antioxidant and free radical scavenging activities of sea buckthorn mixture were evaluated using DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. The leaf extract with fruit juice in the ratio of 60 : 40 (w/w) showed a significant effect (86.43%). The mixture of sea buckthorn leaf and fruit were investigated for anti-inflammatory activity using LPS stimulated Raw 264.7 cells. The results showed that the higher ratio of leaf extract indicated greater anti-inflammatory activity (approximately 10%, NO production ). Conclusion : These result showed that the mixture of sea buckthorn leaf and fruit can be used as a variety of antioxidant and other functional product research and development processes as valuable natural materials.
