Objective : This study examined the impact of a sixteen-week time-use intervention perio on the depression and rehabilitation motivation of stroke patients with psychological difficulties.Methods : Ten stroke patients who were divided into an experimental group and a control group participated in this study from May 2014 to August 2014. Depression changes were measured using a Beck Depression Inventory (BDI), and their rehabilitation motivation was evaluated using the Rehabilitation Motivation Scale.Results : The results of the present study showed that the experimental group and control group presented significant differences before and after intervention in terms of their depression and rehabilitation motivation. However, after intervention, the depression and rehabilitation motivation did not differ between the two groups.Conclusion : The results of this study indicate that time-use intervention was effective in improving the depression and rehabilitation motivation of stroke patients, and therefore time-use intervention with occupational therapy will be useful as a clinical method for improving their level of depression and rehabilitation motivation.