Although the Hazen-Williams C factors are very important in the design, operation, and maintenance of water supply pipes, sufficient studies for them have been not reported in korea, which are based on experiments or measured data. Because of this, we have estimated C factors by measurement considering constraints in time precise safety diagnosis for multi-regional water supply system were performed. In this study, we confirmed constraints and variables characteristics of Hazen-Williams equation, and collected reliable C factors data of 174 by measurement, and analyzed their characteristics. According to collected data, the average value is 115.35, which is almost equal to the value of design standard or a little higher than it in korea. Also, among the equations suggested to determine C factor in the past, the C factors calculated by Sharp and Walski equation was closest to them in this study. In addition, to analyze collected C factors, use year and pipe diameter having high correlation with them were respectively divided into there categories. Analysis results showed that C factors evidently decreases depending on increases in use year, on the other hand, size of pipe diameter is proportional to value of them. In conclusion, this research showing evaluation and characteristics for C factors based on measured data will be used as practical reference in determining C factor in multi-regional water supply systems at a later date.