Therapy with appropriate antimicrobial agents is an important component in the management of patients with liver, biliary and pancreatic infection. Acute cholangitis and cholecystitis are common conditions that may result in progressively severe infection. Infectious complications, both pancreatic (infected necrosis) and extrapancreatic (pneumonia, cholangitis, bacteremia, urinary tract infections, and so on), are a major cause of morbidity and mortality in patients with acute pancreatitis. Antimicrobial agents appropriate for initial therapy (empirical therapy or presumptive therapy) for various grades of severity of infections should be used. Local antimicrobial susceptibility patterns should be considered for use.

• 김용석(건양대학교 의과대학 내과학교실) | Yong Seok Kim Corresponding author