To evaluate therapeutic efficacy of aldose reductase (AR) inhibition, the leaves of Aster yomena were tested for inhibition of AR. The stepwise polarity fractions of A. yomena were tested. Among them, the n-BuOH fraction showed highest activities against AR inhibition. Our results demonstrated that A. yomena could be a worthy natural source source for curing against diabetic complications.

• Sanghoon Yang(Department of Integrative Plant Science, Chung-Ang University, Anseong 456-756, Korea)
• Jaemin Lee(Department of Integrative Plant Science, Chung-Ang University, Anseong 456-756, Korea)
• Sunghun Cho(Department of Integrative Plant Science, Chung-Ang University, Anseong 456-756, Korea)
• Eun Ha Kim(Gurye Agricultural Technology Center, Gurye 604-806, Korea)
• Yeon Kwon Jung(Gurye Agricultural Technology Center, Gurye 604-806, Korea)
• Kung-Woo Nam(Department of Life Science and Biotechnology, Soon Chun Hyang University, Asan 336-745, Korea)
• Sanghyun Lee(Department of Integrative Plant Science, Chung-Ang University, Anseong 456-756, Korea)