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Tyrosinase and α-Glucosidase Inhibitory Activities and Antioxidant Effects of Extracts from Different Parts of Hypochaeris radicata

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한국약용작물학회지 (Korean Journal of Medical Crop Science)
한국약용작물학회 (The Korean Society of Medicinal Crop Science)
초록

Background: Invasion of these invasive plants in the ecosystem threatens the habitat of endemic species, reduces biodiversity, and causes a disturbance in the ecological system. Hypochaeris radicata L. (Asteraceae), the most invasive plant in Korea, particularly in Jeju Island, invades farmlands, and autochthonous forests, resulting in the establishment of monocultures and modification of the ecosystem structure. Methods and Results: In this study was, we evaluated the biological activity of 70% ethanolic extracts from different parts of Hypochaeris radicata L. The biological activities of 70% ethanolic extracts of different parts, such as flower, leaf, stem, and root, of H. radicata were investigated. The total polyphenol content was highest in flower extracts (50.82 ± 3.16 ㎎ · GAE/g). In addition, the highest flavonoid content was observed in flower extract (15.19 ± 2.03㎎ · QE/g). The flower extract of H. radicata exhibited stronger DPPH radical-scavenging activities, ABTS radical scavenging activities, and reducing power than the other parts. The flower extract of H. radicata was observed to have the highest tyrosinase and α-glucosidase inhibitory activities. Conclusions: The flower extracts of H. radicata exhibited remarkable antioxidant activity as well as tyrosinase and α-glucosidase inhibitory effects. These activities might be related to the phenolic compounds present in the H. radicata flower extract.

저자
  • 고현민(제주대학교 생명자원과학대학 친환경농업연구소) | Hyun Min Ko
  • 엄태길(제주대학교 아열대/열대생물 유전자은행센터) | Tae Kil Eom
  • 송선경(제주대학교 생명자원과학대학 친환경농업연구소) | Seon Kyung Song
  • 조가영(제주대학교 생명자원과학대학 친환경농업연구소) | Ga Yeong Jo
  • 김주성(제주대학교 생명자원과학대학 친환경농업연구소) | Ju Sung Kim