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Effect of Achyranthis Radix and Drynariae Rhizoma Extracts on Antioxidant Activity and Antioxidant Enzymes

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한국자원식물학회지 (Korean journal of plant resources)
한국자원식물학회 (The Plant Resources Society Of Korea)
초록

In vitro and in vivo experiments using Achyranthis radix and Drynariae rhizoma extracts were conducted. Antioxidant properties were analyzed and the effects on bone, glucose and lipid metabolism were investigated. Drynariae rhizoma (64.67%) obtained higher DPPH radical scavenging activity compared to Achyranthis radix (19.03%). Similar results were obtained in the reducing power. No differences were observed on the ABTS radical scavenging ability and SOD. In contrast, Achyranthis radix (77.60%) has higher chelating ability compared to Drynariae rhizoma (46.21%). In vivo experiments revealed higher plasma TBARS in OVX-DR than in OVX-AR. Opposite result was seen in erythrocyte TBARS. Hepatic, nephritic and erythrocyte enzymes were considered for the antioxidant enzyme activities. GSH-Px and PON of hepatic enzymes were higher in OVX-AR. While the CAT and GR were higher in OVX-DR. SOD, GSH-Px, GR and PON of nephritic enzymes of OVX-DR were higher compared to OVX-AR. Almost similar values were obtained in CAT using both extracts. The OVX treated rats obtained higher CAT and GR in the erythrocyte enzymes compared to SHAM. The SOD of erythrocyte enzymes in OVX-DR was higher compared to OVX-AR. On the other hand, the GSH-Px was higher in OVX-AR.

저자
  • 강미영(경북대학교 생활과학대학 식품영양학과) | Mi Young Kang (Department of Food Science and Nutrition, Kyungpook National University)
  • 이수현(경북대학교 생활과학대학 식품영양학과) | Soo Hyun Lee (Department of Food Science and Nutrition, Kyungpook National University)
  • 이상원(농촌진흥청 국립원예특작과학원 약용작물과) | Sang Won Lee (Department of Herbal Crop Research, NIHHS, RDA)
  • 차선우(농촌진흥청 국립원예특작과학원 약용작물과) | Sun Woo Cha (Department of Herbal Crop Research, NIHHS, RDA)
  • 송재림(경북대학교 농업생명과학대학 응용생명과학부) | Jae Lim Song (Collage of Agriculture & Life Sciences, Kyungpook National University)
  • 이상철(경북대학교 농업생명과학대학 응용생명과학부) | Sang Chul Lee (Collage of Agriculture & Life Sciences, Kyungpook National University) Corresponding author