A climate change has been reported as the most important issue related with vector borne diseases eg. Zika and Denguemainly transmitted by Aedes mosquitoes. In 2016, 24 imported Zika virus disease cases and > 300 cases of Dengue feverwere reported in the Republic of Korea (ROK). In the ROK, the control of disease vectors has been mainly carried outusing chemicals, which resulted in high insecticide resistance. Many studies and projects in Korea Center for DiseaseControl & Preventionfor overcoming the insecticide resistance of disease vectors have been carried out and some nationaldisease vector management systems for effective vector control are established throughout the ROK. In this presentation,the national vector management systems and studies will be addressed.Key words : Disease vectors, National management, the Republic of Korea, climate change