Recently, it has been reported that plants produce variety of phytochemicals against insect pests as a part of their defencemechanism. In this study, to identify novel compounds that disrupt juvenile hormone (JH) receptor complex, plant essentialoil compounds were tested using in vitro yeast two-hybrid system transformed with the Aedes aegypti JH receptor complex.Among the plant essential oil compounds, farnesol interfered with pyriproxyfen-mediated binding of A. aegypti Met-FISC.In contrast, farnesyl acetate induced the binding of A. aegypti Met-FISC. Also, both compounds caused retardation ofovarian development and change of transcription level in female A. albopictus. These results could provide insights onthe plant-insect coevolution and may be useful for the development of insect specific and safe pesticides.

• Dong Hwan Park(Department of Agricultural Biotechnology, Seoul National University)
• Jae Young Choi(Research Institute for Agriculture and Life Sciences, Seoul National University)
• Seok-Hee Lee(Department of Agricultural Biotechnology, Seoul National University)
• Ying Fang(Department of Agricultural Biotechnology, Seoul National University)
• Jong Hoon Kim(Department of Agricultural Biotechnology, Seoul National University)
• Min Gu Park(Department of Agricultural Biotechnology, Seoul National University)
• Ra Mi Woo(Department of Agricultural Biotechnology, Seoul National University)
• Bo Ram Lee(Department of Agricultural Biotechnology, Seoul National University)
• Woo Jin Kim(Department of Agricultural Biotechnology, Seoul National University)
• Yeon Ho Je(Department of Agricultural Biotechnology, Seoul National University)