This research is devoted to the development of methods general and standard methodological approaches and approbation those for the evaluation of economic potential and level of concentration of the regions of Kazakhstan. This paper presents the results of development of the authors on the selection and justification of the methodological approaches for quantitative evaluation of the economic potential (the degree of territorial differentiation of the profile) and concentration of regions. In this study, we used scientific methods: method of analysis the main trends of economic development, and method of evaluation of concentration of the region. Based on the analysis of foreign techniques developed and tested methodical approaches to the assessment of the economic potential (index and coefficient methods). Proposed methodological approaches to the assessment profile of the territory and developed a system of indicators, which includes an aggregated index of spatial concentration, which accurately reflects the concentration of production in the region. This study shows the results of the analysis of the potential regional disparities and trends of economic development of Kazakhstan. By using, the proposed methodology shows the possibility of their use; we calculated the indicators of integrated assessment of the economic potential and indicators of spatial concentration.

1. Introduction
 2. Theoretical Background and  Literature Review
 3. Methodology of Research
 4. Conclusions

• Nailya K. Nurlanova(Institute of Economics of the Ministry of Education and Science of the Republic of Kazakhstan)
• Anel A. Kireyeva(Chief Scientist. Institute of Economics of the Ministry of Education and Science of the Republic of Kazakhstan) Corresponding Author.
• Rashid M. Ruzanov(Chief Scientist. Institute of Economics of the Ministry of Education and Science of the Republic of Kazakhstan)