In the last decade, more natural disasters have occurred than before in the world. The ASEAN regions are particularly prone to such disasters. Natural disasters can happen anytime and will be a more serious problem in an armed conflict area. In disaster management, humanitarian assistance of the international community is basically subject to the principle of state sovereignty. In a conflict area, however, the principle of sovereignty must be harmonized with the doctrine of responsibility to protect. How could the ASEAN countries accept the doctrine of the responsibility to protect during natural disaster management in an armed conflict? This paper aims to analyze the doctrine of responsibility to protect in the course of managing natural disaster of an armed conflict area in terms of lessons from the ASEAN countries such as Indonesia, Myanmar and the Philippines.