Medici history (1400-1748) covers the time when the political power in Europe gradually shifted from the divided states of Italy to the northern countries. During this period, Medici influence was essential to the development of Florentine cultural and political aspirations. Understanding of Medici musical patronage is spotty throughout the course of Italian history. This article, thus, focuses on the musical support of the Medici family during the Renaissance era. Some of the music produced by the composers sponsored by the Medici family includes works in styles new at the beginning of the Baroque period. This is illustrated in the list of intermedios and operas related to the Medici family. Marco da Gagliano's religious motet preserved in the last part of this study also reveals such a tendency.