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Antimicrobial resistance and virulence genes of Salmonella isolates from chicken industry KCI 등재

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예방수의학회지 (Journal of Preventive Veterinary Medicine)
한국예방수의학회(구 한국수의공중보건학회) (The Korean Society of Preventive Veterinary Medicine)
초록

The ability of antimicrobial resistant Salmonella strains to cause invasive disease can be attributed to various virulence genes. In this study, the virulence genes located in SPI-1, SPI-2, SPI-5, SPI-11 were found in all antimicrobial-resistant Salmonella isolates. This suggests that these genes play important roles in Salmonella invasion, growth, or survival in the host. The association between the presence of virulence genes and antimicrobial resistance was assessed using the Spearman’s correlation coefficient, and there is a positive association between the gatC, tcfA, hylE, spiA, pagC, msgA, invA, sipB, prgH, spaN, orgA, tolC, iroN, sitC, lpfC, and sopB genes, and resistance to CF, NA and S. This suggests that the association between antimicrobial agents and virulence genes has been shown to vary with the types of antibiotics that are commonly used in different countries. These different associations can be explained by the mechanisms underlying pathogenicity and the acquisition of resistance genes by Salmonella.

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ACKNOWLEDGEMENTS
 REFERENCES
저자
  • Young Ju Lee(Department of Public Health, College of Veterinary Medicine, Kyungpook National University) Corresponding Author
  • Jin Eui Kim(Department of Public Health, College of Veterinary Medicine, Kyungpook National University)