Agarooligosaccharides were produced by β-agarase from Bacillus cereus ASK 202. LD_(50) of Agarooligosaccharides was determined to be 1359 mg/kg which corresponded to GRAS material. Agarooligosaccharides at 5% level exhibited 88.3% inhibition on TA98 and 54% on TA100, indicating agarooligosaccharides to be potent antimutagenic substance. Immunologic activity of agarooligosaccharides was also confirmed by mouse spleen cell culture. Agarooligosaccharides addition of 200 ㎕/ml stabilized spleen cells (2.5 × 10^6 cells/ml) as compared to control (6.4 × 10⁴ cells/ml).

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