In this paper, the changing of durability design variables such as cover depth, surface chloride content, and replacement ratio of GGBFS are considered, and optimum substitution ratio of GGBFS are derived with intended service life. With increasing cover depth, service life increased by 2.78~3.21 times. Cover depth is the most influencing parameters of those in this study. For reasonable durability design of concrete, quantitative exterior condition and critical chloride content should be determined.