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Analysis of Differences in Fractional Anisotropy of Diffusion Tensor Images of Basal Ganglia in the Brain Gray Matter according to Smoking KCI 등재

뇌 회백질 기저핵 부위의 흡연유무에 따른 확산텐서 비등방도 측정값 차이분석

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Journal of the Korean Society of Radiology (한국방사선학회논문지)
한국방사선학회 (The Korea Society of Radiology)
초록

흡연 유무의 남성을 대상으로 뇌 회백질의 손상 유무를 파악 할 수 있는 확산텐서영상을 검사하여 영상을 획득 한 후 Tract-Based Spatial Statics(TBSS)방법으로 뇌 회백질 부위의 기저핵 신경섬유로의 비등방도 FA(fractional anisotropy)값을 측정 분석한 결과 모든 영역에서 흡연자가 비흡연자보다 비등방성 측정값이 낮게 관찰되었으며 FA값은 통계적으로 유의하였다. 본 연구의 측정한 FA결과 값으로 추측하자면 즉, 흡연이 뇌 회백질 기저핵의 모든 해부학적 미세 구조성 변화에 크게 영향을 미치며 신경 섬유로를 손상시키고 이와 관련된 기능적 이상에 영향을 준다고 할 수 있다.

The fractional anisotropy value of the basal ganglia fibers in the brain gray matter region was analyzed by Tract-Based Spatial Statics(TBSS) method after acquiring the diffusion tensor image to identify the presence or absence of brain white matter damage to smoking in male. As a result of measurement analysis, the fractional anisotropy measurement value was lower in smokers than non–smokers in all areas, and the FA value was statistically significant. smoking significantly affects all the anatomic micro structural changes in the brain gray matter and damages the nerve fiber tract. As a result, it can affects functional abnormalities related to the minute changes of the brain due to smoking.

목차
ABSTRACT
 I. INTRODUCTION
 II. MATERIAL AND METHODS
  1. 연구대상 및 방법
  2. 검사장비
  3. 뇌 확산텐서 영상 Parameter
  4. 뇌 확산텐서 영상의 분석방법
 III. RESULT
  1. 연구대상의 인구 사회학적 특성별 분포
  2. 흡연에 따른 뇌 백질 부위의 FA값 One-way ANOVA
 IV. DISCUSSION
 V. CONCLUSION
 Reference
 요 약
저자
  • Jong Hyeok Kwak(Department of Radiology, Pusan National University hospital of Yang San) | 곽종혁
  • Bong Kyeong Son(Department of Radiology, Pusan National University hospital of Yang San) | 손봉경
  • Jae Beom Jeong(Graduate School of Health Sciences, Busan Catholic University) | 정재범
  • Soon Ki Sung(Gamma knife center, Pusan National University Hospital of Yang San) | 성순기
  • Seong Jin Kim(Gamma knife center, Pusan National University Hospital of Yang San) | 김성진
  • Dong Won Kang(Department of Radiology, Pusan National University hospital of Yang San) | 강동원
  • Chan Hyeok Park(Department of Radiology, Pusan National University hospital of Yang San) | 박찬혁
  • Hyeon Wha Im(Department of Nursing, Choonhae College of Health Sciences) | 임현화
  • Yu Hui Lee(Department of Dental Hygiene, Choonhae College of Health Sciences) | 이유희
  • Bong Sang Lee(Graduate School of Health Sciences, Inje university) | 이상봉
  • Dong hyeon Kim(Graduate School of Health Sciences, Busan Catholic University) | 김동현 Corresponding Author